Wan2.2-S2V is a powerful AI workflow that generates realistic talking avatar videos from audio and images. This guide explains how to install Wan2.2-S2V, set up all required models, and start creating natural lip-sync video avatars using ComfyUI on your local machine.
What is Wan2.2-S2V?
Wan2.2-S2V is an open-source workflow designed for ComfyUI. It converts audio recordings and still images into talking video avatars with natural lip-sync and expressive facial movements. This tool is ideal for content creators, educators, marketers, and anyone who wants to create professional AI video presentations locally.
Example outputs — what Wan2.2-S2V can generate
Download the Wan2.2-S2V Workflow
Download the ready-to-use workflow JSON file below. This file is pre-configured with all node connections — just load it into ComfyUI and select your model files.
Drag and drop this JSON file into your ComfyUI canvas to load it instantly.
Download Required Wan2.2-S2V Models
Make sure you download all five required model files and place them in the correct folders inside your ComfyUI/models/ directory before running the workflow.
Diffusion Model (choose one)
- wan2.2_s2v_14B_fp8_scaled.safetensors (recommended — lower VRAM)
- wan2.2_s2v_14B_bf16.safetensors (higher quality — needs more VRAM)
VAE
Text Encoder
LoRA
Audio Encoder
Folder Structure — Where to Place All Files
Place your downloaded models exactly like this:
ComfyUI/
└── models/
├── diffusion_models/
│ ├── wan2.2_s2v_14B_fp8_scaled.safetensors
│ └── wan2.2_s2v_14B_bf16.safetensors
├── vae/
│ └── wan_2.1_vae.safetensors
├── text_encoders/
│ └── umt5_xxl_fp8_e4m3fn_scaled.safetensors
├── audio_encoders/
│ └── wav2vec2_large_english_fp16.safetensors
└── loras/
└── lightx2v_I2V_14B_480p_cfg_step_distill_rank256_bf16.safetensorsaudio_encoders folder — this is unique to S2V and different from standard ComfyUI setups. Create it if it doesn't exist inside ComfyUI/models/.Step-by-Step Setup Guide to Install Wan2.2-S2V
Follow these seven steps to get Wan2.2-S2V running inside ComfyUI on your local machine.
Update ComfyUI
Import the Workflow
Place All Model Files
ComfyUI/models/ as shown in the folder structure.Configure Nodes in ComfyUI
- Load Diffusion Model:
wan2.2_s2v_14B_fp8_scaled.safetensors(or bf16) - Load Audio Encoder:
wav2vec2_large_english_fp16.safetensors - Load CLIP:
umt5_xxl_fp8_e4m3fn_scaled.safetensors - Load VAE:
wan_2.1_vae.safetensors - Load LoRA:
lightx2v_I2V_14B_480p_..._bf16.safetensors
Add Your Audio, Image, and Prompt
Adjust Settings (Optional)
Run the Workflow
Example Run
Here is a real example generated with Wan2.2-S2V in ComfyUI using the prompt below. Click the video to play it.
Prompt Used
Tips & Troubleshooting
If something isn't working as expected, these are the most common causes and fixes:
Video generation is slow
Fix: Lower the output resolution or reduce the number of sampler steps. Use the fp8 diffusion model variant instead of bf16 — it significantly reduces VRAM usage and generation time.
Audio not syncing well with lip movements
Fix: Use clear, high-quality mono audio clips with minimal background noise. Noisy or compressed audio reduces lip-sync accuracy. Try trimming the clip to 8–15 seconds first.
Crashes or CUDA out-of-memory errors
Fix: Double-check all model files are in the correct folders. Reduce resolution and step count. Switch to the fp8 diffusion model if you're using bf16. Make sure the audio_encoders folder exists and contains the wav2vec2 file.
Output looks unnatural or stiff
Fix: Refine your prompt to describe gestures and expressions more precisely. Include phrases like 'natural eye contact', 'slight hand gestures', and 'upright posture' for more lifelike results.
Model files not appearing in node dropdowns
Fix: After placing new files in ComfyUI folders, press F5 or Ctrl+Shift+R to fully refresh ComfyUI in your browser. New files will not appear until a full refresh.
Conclusion
Wan2.2-S2V makes it easy to create realistic talking avatar videos from your audio and images using AI — entirely locally, with no subscription required. By following this guide, anyone can install Wan2.2-S2V, set up the necessary models, and start generating professional-quality video presentations in ComfyUI. The fp8 model keeps VRAM requirements manageable for mid-range GPUs.
Frequently Asked Questions
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